What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Zetia (Ezetimibe)

Also Known as Ezetrol


Zetia (Ezetimibe)

Prescription Required


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Generic Equivalent - Zetia (Ezetimibe)

Prescription Required


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  • Product Details


    ZETIA (ezetimibe) is a medication prescribed to treat different conditions related to high cholesterol. It can be prescribed for the following:

    • Familial hypercholesterolemia in combination with atorvastatin or simvastatin
    • Homozygous sitosterolemia
    • Mixed hyperlipidemia in combination with fenofibrate
    • Primary hyperlipidemia alone or in combination with a statin medication

    ZETIA medication is primarily used to reduce levels of different types of cholesterol in patients whose cholesterol levels are elevated. High levels of certain types of cholesterols are linked to increased cardiovascular events and death. ZETIA can lower these cholesterols but it has not been linked to a reduction in morbidity and mortality of cardiovascular outcomes.

    ZETIA works by preventing the absorption of cholesterol in the small intestine. Cholesterol is absorbed in the small intestine from the diet and when it is secreted by the body in the bile. ZETIA’s target protein is the Niemann-Pick C1-Like 1 (NPC1L1) sterol transporter, which is responsible for absorbing cholesterol in the small intestine.


    Take Zetia 10 mg by mouth once daily with or without food.


    The active ingredient in ZETIA is ezetimibe, which is also the name for ZETIA generic.


    Speak with your doctor if you have moderate or severe impairment of the liver. 

    If you are taking ZETIA with a statin medication, your doctor should monitor the levels of your liver enzymes.

    Tell your doctor if you experience muscle aches or cramping while taking either ZETIA alone or ZETIA in combination with a statin medication.

    Side Effects

    Some of the most common adverse effects of ZETIA may include:

    • Arthralgia
    • Diarrhea
    • Myalgia
    • Nasopharyngitis
    • Pain in extremities
    • Sinusitis
    • Upper respiratory infection

    Speak with your doctor or pharmacist for a full list of side effects that may apply to you. If you experience muscle aches or pains while taking ZETIA, call your doctor immediately.


    1. Zetia [package insert]. Whitehouse Station, NJ: Merck; 2012.
    2. Arthralgia, Johns Hopkins Medicine. Retrieved May 2020.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 2438

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