A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Axid (Nizatidine)
Brand
Axid (Nizatidine)
Prescription Required
Strength
Qty
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Axid is an oral medication that your healthcare provider may prescribe to treat painful stomach conditions. It is commonly prescribed for gastrointestinal reflux disease (GERD), benign gastric ulcer, duodenal ulcer, and Helicobacter pylori infection.
These conditions commonly cause symptoms like eructation (burping), heartburn, nausea, abdominal discomfort, and bitter taste in the mouth.
Axid is a histamine receptor antagonist and works on histamine receptors on the surface of stomach cells. By blocking histamine receptors, Axid reduced the amount of stomach acid secreted by stomach cells.
Fact Table
Formula
C12H21N5O2S2
License
US FDA
Bioavailability
More than 70%
Legal status
US: OTC / Rx-only
Chemical Name
Nizatidine
Elimination half-life
1–2 hours
Dosage (Strength)
150mg, 300mg
Pregnancy
Not Recommended
Brands
Axid, Tazac
Protein binding
35%
PubChem CID
3033637
MedlinePlus
a694030
ChEBI
7601
ATC code
A02BA04
DrugBank
DB00585
KEGG
D00440
Routes of administration
By mouth
Directions
For the treatment of duodenal ulcer or gastric ulcer, the starting dosage is 150 mg by mouth twice daily. It can be increased to 300 mg twice daily. A full course may last up to 8 weeks. Some doctors may have you continue Axid 150 mg once daily for long-term maintenance.
For the treatment of GERD, the standard dosage is 150 mg twice daily for 12 weeks.
To treat Helicobacter pylori infection, the standard dosage of Axid 150 mg twice daily for 10-14 days in combination with other medications.
Ingredients
Axid generic is called nizatidine, which is the active ingredient in the medication.
Interactions
Common drug-drug interactions with Axid medications can include:
Atazanavir
Cefpodoxime
Cefuroxime
Dasatinib
Erlotinib
Fosamprenavir
Gefitinib
Indinavir
Ketoconazole
Multivitamins/Minerals
Nilotinib
Octreotide
Posaconazole
Rilpivirine
Risedronate
Saquinavir
Varenicline
Velpatasvir
Tell your doctor and pharmacist about all medications you are taking before starting Axid.
Cautions
Long-term usage may lead to vitamin B12 deficiency. This effect is more likely to occur in females under 30 years of age.
Use with caution if you have a history of kidney problems.
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 1362
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