What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Crestor (Rosuvastatin Calcium)
Generic Equivalent - Crestor (Rosuvastatin Calcium)
Prescription Required
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Product Details
Description
CRESTOR (rosuvastatin calcium) is a medication prescribed to treat low cholesterol in patients with one or all of the following conditions:
- Atherosclerosis, to slow the progression
- History of heart attack, stroke, or arterial revascularization in patients with congenital heart disease (CHD)
- Primary hyperlipidemia and mixed dyslipidemia
- Hypertriglyceridemia
- Dysbetalipoproteinemia
- Homozygous familial hypercholesterolemia
CRESTOR works by inhibiting HMG-CoA reductase, which is an enzyme that helps to produce mevalonate, a precursor of cholesterol. CRESTOR also works by reducing the number of LDL (low-density lipoprotein) and VLVL (very low-density lipoprotein).
Reducing cholesterol has been shown to lower the chance of cardiovascular events like heart attack and stroke.
Fact Table
Formula
C22H28FN3O6S
License
FDA approved
Bioavailability
Approximately 20%
Legal status
Prescription only (Rx Only)
Chemical Name
Rosuvastatin Calcium
Elimination half-life
19 hours
Dosage (Strength)
Tablets: 5 mg, 10 mg, 20 mg, 40 mg
Pregnancy advice
Contraindicated
Brands
Crestor
Protein binding
~90%
PubChem CID
446157
MedlinePlus
a603035
ChEBI
CHEBI:38545
ATC code
C10AA07
DrugBank
DB01098
KEGG
D01915
Routes of administration
Oral
Directions
For adults, the normal dose range of CRESTOR is 5 mg to 40 mg by mouth once daily. CRESTOR can be taken with or without food and can be taken at any time of day.
In pediatric patients between the ages of 10 to 17, the normal dose range is 5 mg to 20 mg by mouth once daily with or without food. Doses above 20 mg have not been studied in pediatric patients.
Ingredients
The active ingredient in Crestor is rosuvastatin calcium, which is also the name for CRESTOR generic.
Cautions
CRESTOR and other statin medications can cause a serious side effect called rhabdomyolysis, which is the abnormal breakdown of muscle tissue. Tell your doctor or pharmacist if you experience muscle aches and weakness while taking CRESTOR. Other symptoms may include muscle pain, tenderness, and dark urine.
Your doctor should monitor your liver enzymes while you are taking CRESTOR because it can cause transient increases in liver enzymes.
Side Effects
Some of the most common adverse effects may include:
- Abdominal pain
- Asthenia
- Headache
- Myalgia
- Nausea
Buy CRESTOR online from Canada Pharmacy and skip the wait at the local pharmacy. CRESTOR can be purchased with a valid prescription from a licensed healthcare provider.
References
- Crestor [package insert]. Wilmington, DE: IPR Pharmaceuticals; 2010.
- Statin Medications, MedicineNet, November 25th, 2019. Retrieved May 2020.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 2328
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