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Dovonex Cream (Calcipotriol)

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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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  • Product Details

    Description

    Dovonex is a prescription cream that your doctor may prescribe to treat plaque psoriasis. This medication is usually prescribed by a dermatologist or other specialists specifically trained in treating skin disorders.

    Psoriasis is a skin disease where a person develops red, scaly, and itchy patches. The patches most commonly appear on the trunk, scalp, elbows, and knees. There are different types of psoriasis, and plaque psoriasis is the most common.

    Symptoms of plaque psoriasis can include dry and scaly lesions that are often covered with silvery scales. The patches are usually itchy and tender.

    Fact Table

    Formula

    C27H40O3

    License

    US DailyMed

    Bioavailability

    5 to 6%

    Legal status

    Rx-Only

    Chemical Name

    Calcipotriol

    Elimination half-life

    Less than 10 min

    Dosage (Strength)

    0.005%

    Pregnancy

    Consult Doctor

    Brands

    Dovonex Cream

    Protein binding

    Unknown

    PubChem CID

    5288783

    MedlinePlus

    a608018

    ChEBI

    50749

    ATC code

    D05AX02

    DrugBank

    DB02300

    KEGG

    D01125

    Routes of administration

    Topical administration

    Directions

    Dovonex cream is usually applied to the skin twice daily as directed by the healthcare provider.

    Wash and dry your hands before and after applying Dovonex.

    Do not apply this medication at the same time as other topical medications.

    Ingredients

    The active ingredient in Dovonex is calcipotriene.

    Inactive ingredients include cetearyl alcohol, ceteth-20, diazolidinyl urea, dichlorobenzyl alcohol,

    dibasic sodium phosphate, edetate disodium, dl-alpha tocopherol, glycerin, mineral oil, petrolatum, and water.

    Interactions

    Drug-drug interactions with this medication include:

    • Calcium salts
    • Chlorthalidone
    • Digoxin
    • Hydrochlorothiazide
    • Lactic acid
    • Multivitamins
    • Salicylic acid
    • Sucralfate
    • Thiazide
    • Topical hydrocortisone
    • Vitamin D analogs

    Cautions

    Dovonex cream may worsen certain types of dermatitis.

    Dovonex cream may increase the amount of calcium in your body. Your doctor should periodically check for increases.

    Stop Dovonex cream if irritation occurs around the application site.

    Side Effects

    Common adverse reactions may include:

    • Allergic contact dermatitis
    • Application site pain
    • Application site reaction
    • Burning sensation of skin
    • Dermatitis
    • Desquamation
    • Erythema of skin
    • Exacerbation of psoriasis
    • Folliculitis
    • Hypercalcemia
    • Hyperpigmentation
    • Pruritus 
    • Psoriasis
    • Skin atrophy
    • Skin irritation
    • Skin rash
    • Stinging of the skin
    • Tingling of skin
    • Xeroderma

    References


    Dovonex [package insert]. Dublin, Ireland: LEO Laboratories; 2015.


    Frequently Asked Questions about Dovonex Cream (Calcipotriol)

    What is Dovonex Cream (Calcipotriol)?

    Dovonex Cream is a topical medication that contains the active ingredient calcipotriol. It is used to treat certain skin conditions, particularly psoriasis.

    What skin conditions does Dovonex Cream treat?

    Dovonex Cream is primarily prescribed for the treatment of psoriasis, a chronic skin condition characterized by red, scaly patches. It can help reduce the symptoms of psoriasis by slowing down the growth of skin cells.

    How does Dovonex Cream work?

    Dovonex Cream works by controlling the excessive growth of skin cells and reducing inflammation associated with psoriasis. It affects the way skin cells behave and helps alleviate the symptoms of this condition.

    Is Dovonex Cream available over the counter (OTC)?

    No, Dovonex Cream is not available over the counter. It is a prescription medication, which means you need a doctor's prescription to obtain it.

    Are there any potential side effects of using Dovonex Cream?

    Like any medication, Dovonex Cream may have side effects. Common side effects include skin irritation, burning, itching, and dryness at the application site. These side effects are usually mild and temporary. However, if you experience severe or persistent side effects, consult your healthcare provider.

    How should I apply Dovonex Cream?

    Follow your doctor's instructions carefully. Generally, you should apply a thin layer of Dovonex Cream to the affected areas of your skin once or twice daily. Gently rub it in until it is absorbed. Wash your hands after application, unless you are treating psoriasis on your hands.

    Can I use Dovonex Cream during pregnancy or while breastfeeding?

    It is essential to consult your healthcare provider before using Dovonex Cream during pregnancy or while breastfeeding. They can assess the risks and benefits and recommend the most appropriate treatment plan for you.

    How long does it take to see results with Dovonex Cream?

    The time it takes to see improvement can vary from person to person. Some individuals may notice positive effects within a few weeks, while others may require several weeks of consistent use. It's important to follow your doctor's recommended treatment plan and be patient.

    Can I use other skincare products alongside Dovonex Cream?

    You should consult your doctor before using other skincare products alongside Dovonex Cream. Some products may interact with Dovonex or affect its effectiveness.

    Can Dovonex Cream be used on the face?

    Dovonex Cream is typically not recommended for use on the face unless specifically prescribed by your doctor. Facial skin is more sensitive, and there may be other treatments better suited for facial psoriasis.


    Dr Conor Sheehy
    About Dr. Conor Sheehy (Page Author)

    Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 1492

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