What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Loprox (Ciclopirox)

Also Known as Nibulen


Loprox (Ciclopirox)

Prescription Required

1% Cream
1% Lotion

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  • Product Details


    LOPROX (ciclopirox) is a prescription medication that is used for fungal infections. It is effective against different types of fungal species and can be made into a lotion or a cream.

    • Onychomycosis of the fingernails and toenails
    • Seborrheic dermatitis
    • Tinea cruris
    • Tinea corporis
    • Tinea pedis

    When applied to the skin, LOPROX works by preventing fungal cells from dividing. It interferes with critical molecules in fungal cells like DNA, RNA, and protein. LOPROX may take several weeks to start working and should be continued for at least four weeks.

    Fact Table




    US FDA


    Less than 5%

    Legal status


    Chemical Name


    Elimination half-life

    1.7 hours

    Dosage (Strength)



    No Known Risks



    Protein binding

    94 to 97%

    PubChem CID






    ATC code






    Routes of administration



    The normal instructions for LOPROX are to apply to the affected area(s) of the skin twice daily. Apply to a clean and dry area of the skin. Wash hands thoroughly after application. Do not get LOPROX into the eyes, mouth, or onto the genitals.

    Use LOPROX exactly as prescribed.


    The active ingredient in LOPROX is ciclopirox.


    There are no known drug-drug interactions with LOPROX since it is not absorbed into the bloodstream.


    If irritation or redness develops, stop taking LOPROX and tell your doctor.

    Certain formulations of LOPROX may contain benzoyl peroxide. Large amounts have been associated with gasping syndrome in neonates.

    Side Effects

    Common LOPROX cream side effects may include:

    • Acne vulgaris
    • Alopecia
    • Application site burning
    • contact dermatitis
    • Erythema
    • Facial edema
    • Hair discoloration (shampoo only)
    • Headache
    • Local irritation
    • Local pain
    • Localized erythema
    • Nail disease
    • Ventricular tachycardia (shampoo only)


    Loprox [package insert]. Scottsdale, AZ: Medicis; 2013.

    Frequently Asked Questions about Loprox (Ciclopirox)

    What is Loprox (Ciclopirox)?

    Loprox is a brand name medication that contains the active ingredient ciclopirox. It is an antifungal medication used to treat fungal infections of the skin, such as athlete's foot, jock itch, and ringworm.

    How does Loprox work?

    Loprox works by inhibiting the growth of fungi on the skin. It interferes with the fungal cell membranes, weakening them and ultimately leading to the death of the fungus.

    What types of fungal infections can Loprox treat?

    Loprox is primarily used to treat dermatophyte infections, which include conditions like athlete's foot, jock itch, and ringworm. It may also be prescribed for other fungal infections at the discretion of a healthcare provider.

    Is Loprox available over-the-counter (OTC)?

    Loprox is not typically available over-the-counter. It is usually a prescription medication, and you should consult a healthcare provider to obtain it.

    How should I use Loprox?

    The application instructions for Loprox may vary depending on the type and location of the fungal infection. Generally, it is applied as a cream, gel, or solution to the affected area of the skin. Follow your healthcare provider's instructions and the directions on the prescription label carefully.

    Are there any side effects associated with Loprox?

    Like any medication, Loprox may have side effects. Common side effects can include skin irritation, itching, burning, or redness at the application site. If you experience severe side effects or have concerns, consult your healthcare provider.

    How long should I use Loprox for my fungal infection?

    The duration of Loprox treatment can vary depending on the type and severity of the fungal infection. It's essential to complete the full course of treatment as prescribed by your healthcare provider, even if your symptoms improve before the treatment is finished.

    Can I use other skincare products with Loprox?

    It is advisable to consult your healthcare provider before using other skincare products in conjunction with Loprox. Some products may interact with Loprox or affect its effectiveness.

    Is Loprox safe to use during pregnancy or while breastfeeding?

    If you are pregnant or breastfeeding, discuss the use of Loprox with your healthcare provider. They will assess the potential benefits and risks and provide guidance on its use during these periods.

    Can I use Loprox on open wounds or broken skin?

    Loprox is typically intended for use on intact skin and should not be applied to open wounds or broken skin unless specifically instructed by your healthcare provider. Always follow your doctor's recommendations regarding application.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 1615

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