What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Valtrex (Valacyclovir)
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Product Details
Description
Valtrex is a prescription antiviral that can be used to treat the following conditions:
- Cold sores
- Genital herpes
- Herpes zoster
Valtrex can also be used for viral suppression in patients who are positive for HIV.
Valtrex works by incorporating into an important virus enzyme that helps it to replicate. Once incorporated, viral particles cannot reproduce, and the body can suppress the infection. Valtrex does not cure herpes infection, but it can stop symptoms.
Directions
The dosage of Valtrex depends on why it is being used:
- Cold sores: Take 2 grams by mouth every 12 hours for one day
- Genital herpes, initial episode: Take 1 gram by mouth twice daily for ten days
- Genital herpes, recurrent episode: Take 500 mg by mouth twice daily for three days
- Suppression of HIV: 500 mg by mouth once daily
Take Valtrex exactly as prescribed by the doctor.
The dose may need to be reduced if you have poor kidney function.
Take each dose with a full glass of water to prevent accumulation in the kidneys.
Ingredients
The active ingredient in Valtrex generic is Valacyclovir.
Interactions
Common drug-drug interactions with this medication may include:
- Cladribine
- Clozapine
- Foscarnet
- Mycophenolate
- Tenofovir
- Theophylline
- Tizanidine
- Varicella vaccine
- Zidovudine
- Zoster vaccine
Fact Table
Formula
C13H20N6O4
License
US FDA
Bioavailability
55%
Legal status
US: RX Only
Chemical Name
Valacyclovir
Elimination half-life
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Dosage (Strength)
500mg (42 tablets), 1000mg (42 tablets)
Pregnancy
Consult a doctor
Brands
Valtrex
Protein binding
13-18%
PubChem CID
2764
MedlinePlus
a695010
ChEBI
35854
ATC code
J05AB11
DrugBank
DB00577
KEGG
D00398
Routes of administration
By mouth (tablets)
Cautions
Valtrex should be used with caution in older patients and those with poor kidney function unless directed by your healthcare provider.
Valtrex should not be used for longer than prescribed by your doctor.
Side Effects
Valtrex side effects may include the following:
- Abdominal pain
- Arthralgia
- Decreased hemoglobin
- Dehydration
- Depression
- Diarrhea
- Dizziness
- Dysmenorrhea
- Fatigue
- Fever
- Headache
- Increased liver enzymes
- Increased serum creatinine
- Leukopenia
- Nasopharyngitis
- Nausea
- Neutropenia
- Rhinorrhea
- Skin rash
- Thrombocytopenia
- Vomiting
Tell your doctor if you experience any of the above adverse reactions.
References
- Valtrex [package insert]. Greenville, NC: GlaxoSmithKline; 2008.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1885
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