Description
Valtrex is a prescription antiviral that can be used to treat the following conditions:
- Cold sores
- Genital herpes
- Herpes zoster
Valtrex can also be used for viral suppression in patients who are positive for HIV.
Valtrex works by incorporating into an important virus enzyme that helps it to replicate. Once incorporated, viral particles cannot reproduce, and the body can suppress the infection. Valtrex does not cure herpes infection, but it can stop symptoms.
Directions
The dosage of Valtrex depends on why it is being used:
- Cold sores: Take 2 grams by mouth every 12 hours for one day
- Genital herpes, initial episode: Take 1 gram by mouth twice daily for ten days
- Genital herpes, recurrent episode: Take 500 mg by mouth twice daily for three days
- Suppression of HIV: 500 mg by mouth once daily
Take Valtrex exactly as prescribed by the doctor.
The dose may need to be reduced if you have poor kidney function.
Take each dose with a full glass of water to prevent accumulation in the kidneys.
Ingredients
The active ingredient in Valtrex generic is Valacyclovir.
Interactions
Common drug-drug interactions with this medication may include:
- Cladribine
- Clozapine
- Foscarnet
- Mycophenolate
- Tenofovir
- Theophylline
- Tizanidine
- Varicella vaccine
- Zidovudine
- Zoster vaccine
Fact Table |
Formula |
C13H20N6O4 |
License |
US FDA |
Bioavailability |
55% |
Legal status |
US: RX Only |
Chemical Name |
Valacyclovir |
Elimination half-life |
- |
Dosage (Strength) |
500mg (42 tablets), 1000mg (42 tablets) |
Pregnancy |
Consult a doctor |
Brands |
Valtrex |
Protein binding |
13-18% |
PubChem CID |
2764 |
MedlinePlus |
a695010 |
ChEBI |
35854 |
ATC code |
J05AB11 |
DrugBank |
DB00577 |
KEGG |
D00398 |
Routes of administration |
By mouth (tablets) |
Cautions
Valtrex should be used with caution in older patients and those with poor kidney function unless directed by your healthcare provider.
Valtrex should not be used for longer than prescribed by your doctor.
Side Effects
Valtrex side effects may include the following:
- Abdominal pain
- Arthralgia
- Decreased hemoglobin
- Dehydration
- Depression
- Diarrhea
- Dizziness
- Dysmenorrhea
- Fatigue
- Fever
- Headache
- Increased liver enzymes
- Increased serum creatinine
- Leukopenia
- Nasopharyngitis
- Nausea
- Neutropenia
- Rhinorrhea
- Skin rash
- Thrombocytopenia
- Vomiting
Tell your doctor if you experience any of the above adverse reactions.
References
- Valtrex [package insert]. Greenville, NC: GlaxoSmithKline; 2008.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 1885