What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Wellbutrin XL (Bupropion)


Wellbutrin XL (Bupropion)

Prescription Required


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Generic Equivalent - Wellbutrin XL (Bupropion)

Prescription Required


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  • Product Details


    Wellbutrin XL

    Wellbutrin XL (bupropion extended-release) is a medication prescribed to treat Major Depressive Disorder (MDD) and Seasonal Affective Disorder (SAD). MDD and SAD are mood disorders where a person experiences depressed moods (emptiness, sadness, etc.), decreased interest in normal activity, changes in sleep, changes in diet, low energy, difficulty concentrating, and similar symptoms that last for at least two weeks and often many months.

    Wellbutrin XL works by increasing the levels of neurotransmitters dopamine and norepinephrine in certain parts of the brain. By increasing these neurotransmitters consistently over several weeks, Wellbutrin XL normalizes levels of these neurotransmitters, helping return the mood to normal.

    Fact Table




    EU EMA, US FDA, US DailyMed



    Legal status


    Chemical Name


    Elimination half-life

    11–21 h

    Dosage (Strength)

    150mg, 300mg


    Consult Doctor



    Protein binding


    PubChem CID






    ATC code






    Routes of administration

    By mouth


    Take Wellbutrin XL once daily at the same time each day. The normal dosage ranges from 150-450 mg.

    Note that other formulations of the active ingredient like Wellbutrin (bupropion immediate-release) and Wellbutrin SR (bupropion sustained-release) are not interchangeable with Wellbutrin XL.


    The active ingredient in Wellbutrin XL is bupropion hydrochloride.


    Wellbutrin XL may increase the risk of seizures and should be used with caution in people with epilepsy or a history of seizures.

    In some short-term studies, antidepressants increased the risk of suicidal ideation and action in children and young adults. Since depression itself is associated with suicidal thoughts and behaviors, this should not be a reason to forgo treatment. Friends and family members should be alert to suicidal thoughts and actions in patients that are starting antidepressants, but this risk does not remain over the long-term. Adults over 24 did not show an increased risk.

    Side Effects

    Wellbutrin XL side effects may include:

    • Abdominal Pain
    • Agitation
    • Chest pain
    • Constipation
    • Diarrhea
    • Dizziness
    • Dry Mouth
    • Flushing
    • Insomnia
    • Migraine
    • Migraine
    • Nausea
    • Nausea
    • Palpitation
    • Rash
    • Tremor

    Not everyone who takes Wellbutrin XL experiences every side effects, and most people only experience one or two. Speak with your doctor for a full list of possible side effects.


    1. Wellbutrin XL. [package insert] Research Triangle Park, NC: GlaxoSmithKline; 2009.

    Frequently Asked Questions about Wellbutrin XL

    What is Wellbutrin XL used for?

    Wellbutrin XL is an antidepressant used to treat major depressive disorder and seasonal affective disorder.

    Is Wellbutrin XL a strong antidepressant?

    Wellbutrin XL is considered a moderate-strength antidepressant. Its effectiveness varies from person to person, and it’s essential to consult with a healthcare professional to determine the most suitable treatment for individual needs.

    What are the cons of Wellbutrin XL?

    While Wellbutrin XL can be effective, it has potential side effects. Common ones include dry mouth, blurred vision, nausea, weight loss, and sleep disturbances. Serious side effects may include seizures, changes in mood or behavior, and fast or irregular heartbeats.

    How does Wellbutrin XL make you feel?

    Wellbutrin XL affects individuals differently. Some people experience improved mood, increased energy, and reduced depressive symptoms. However, others may encounter side effects like anxiety, nervousness, or restlessness. It’s essential to monitor your response and communicate any changes to your doctor.

    What is the biggest side effect of Wellbutrin?

    One of the significant side effects of Wellbutrin XL is seizures (convulsions). It may also increase the risk of suicidal thoughts or behavior. Close observation and communication with the prescriber are crucial.

    How fast is weight loss on Wellbutrin XL?

    Weight loss can vary among individuals. Some people may experience gradual weight loss while taking Wellbutrin XL due to its effects on appetite and metabolism. Consult with a healthcare provider regarding any significant changes.

    What happens if you miss a dose of Wellbutrin XL?

    If you miss a dose, take it as soon as you remember. However, if it’s close to the next scheduled dose, skip the missed one. Do not double up on doses. Consult your doctor for specific guidance.

    What happens if you take Wellbutrin and don't need it?

    Taking Wellbutrin when not needed can lead to unnecessary side effects. Always follow your doctor’s recommendations and avoid self-medicating.

    Can I drink while on Wellbutrin?

    Moderate alcohol consumption is generally considered safe while taking Wellbutrin XL. However, excessive alcohol use can increase the risk of seizures and other side effects.

    Does Wellbutrin help with brain fog?

    Wellbutrin XL may improve cognitive function for some individuals, potentially reducing brain fog.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 5494

  • Product Reviews


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