What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Wellbutrin XL (Bupropion)
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Product Details
Description
Wellbutrin XL (bupropion extended-release) is a medication prescribed to treat Major Depressive Disorder (MDD) and Seasonal Affective Disorder (SAD). MDD and SAD are mood disorders where a person experiences depressed moods (emptiness, sadness, etc.), decreased interest in normal activity, changes in sleep, changes in diet, low energy, difficulty concentrating, and similar symptoms that last for at least two weeks and often many months.
Wellbutrin XL works by increasing the levels of neurotransmitters dopamine and norepinephrine in certain parts of the brain. By increasing these neurotransmitters consistently over several weeks, Wellbutrin XL normalizes levels of these neurotransmitters, helping return the mood to normal.
Fact Table
Formula
C13H18ClNO
License
EU EMA, US FDA, US DailyMed
Bioavailability
Unknown
Legal status
Rx-Only
Chemical Name
Bupropion
Elimination half-life
11–21 h
Dosage (Strength)
150mg, 300mg
Pregnancy
Consult Doctor
Brands
Wellbutrin
Protein binding
84%
PubChem CID
444
MedlinePlus
a695033
ChEBI
3219
ATC code
N06AX12
DrugBank
DB01156
KEGG
D07591
Routes of administration
By mouth
Directions
Take Wellbutrin XL once daily at the same time each day. The normal dosage ranges from 150-450 mg.
Note that other formulations of the active ingredient like Wellbutrin (bupropion immediate-release) and Wellbutrin SR (bupropion sustained-release) are not interchangeable with Wellbutrin XL.
Ingredients
The active ingredient in Wellbutrin XL is bupropion hydrochloride.
Cautions
Wellbutrin XL may increase the risk of seizures and should be used with caution in people with epilepsy or a history of seizures.
In some short-term studies, antidepressants increased the risk of suicidal ideation and action in children and young adults. Since depression itself is associated with suicidal thoughts and behaviors, this should not be a reason to forgo treatment. Friends and family members should be alert to suicidal thoughts and actions in patients that are starting antidepressants, but this risk does not remain over the long-term. Adults over 24 did not show an increased risk.
Side Effects
Wellbutrin XL side effects may include:
- Abdominal Pain
- Agitation
- Chest pain
- Constipation
- Diarrhea
- Dizziness
- Dry Mouth
- Flushing
- Insomnia
- Migraine
- Migraine
- Nausea
- Nausea
- Palpitation
- Rash
- Tremor
Not everyone who takes Wellbutrin XL experiences every side effects, and most people only experience one or two. Speak with your doctor for a full list of possible side effects.References
- Wellbutrin XL. [package insert] Research Triangle Park, NC: GlaxoSmithKline; 2009.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 5494
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