What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Indocin (Indomethacin)

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Generic

What is a Generic?

Generic Equivalent - Indocin (Indomethacin)

Prescription Required

Strength
Qty
25mg
50mg

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  • Product Details

    Description

    Your doctor may prescribe indomethacin to treat different types of pain. It can be used for: moderate to severe rheumatoid arthritis, including acute flares of chronic disease, moderate to severe ankylosing spondylitis, moderate to severe osteoarthritis, acute painful shoulder, and acute gouty arthritis.

    The medication belongs to the class non-steroidal anti-inflammatory drugs (NSAIDs). These types of medication are non-narcotic pain medications and can be used for a variety of conditions.

    Fact Table

    Formula

    C19H16ClNO4

    License

    US FDA

    Bioavailability

    ~100%

    Legal status

    Rx-only

    Chemical Name

    Indometacin

    Elimination half-life

    2.6-11.2 hours

    Dosage (Strength)

    25mg, 50mg

    Pregnancy

    Not Recommended

    Brands

    Indocid, Indocin

    Protein binding

    99%

    PubChem CID

    3715

    MedlinePlus

    a681027

    ChEBI

    49662

    ATC code

    C01EB03

    DrugBank

    DB00328

    KEGG

    D00141

    Routes of administration

    By mouth

    Directions

    Take Indomethacin exactly as prescribed by your doctor based on the condition being treated. The standard dosage varies from 25-50 mg up to three times daily.

    Ingredients

    The active ingredient is indomethacin.

    Interactions

    There are many potential drug-drug interactions with indomethacin. Please tell your doctor and pharmacist if you are taking any of the following:

    • Acemetacin
    • Aminolevulinic Acid
    • Apixaban
    • Bemiparin
    • CycloSPORINE 
    • Dabigatran Etexilate
    • Diflunisal
    • Edoxaban
    • Enoxaparin
    • Heparin
    • Ketorolac
    • Lithium
    • Loop Diuretics
    • Macimorelin
    • Methotrexate
    • Mifamurtide
    • Nonsteroidal Anti-Inflammatory Agents
    • Phenylbutazone
    • PRALAtrexate
    • Rivaroxaban
    • Salicylates
    • Selective Serotonin Reuptake Inhibitors
    • Sincalide
    • Sodium Phosphates
    • Tenofovir Products
    • Tenoxicam
    • Tiludronate
    • Triamterene
    • Urokinase
    • Vitamin K Antagonists

    Cautions

    Before starting indomethacin, you should tell your doctor if you have a history of kidney disease, liver disease, heart disease, or heart failure.

    Indomethacin and other NSAIDs should only be used for the shortest amount of time at the lowest possible doses.

    Stop Indomethacin and tell your doctor right away if you develop if skin rash while taking this drug.

    Side Effects

    Some of the most common Indomethacin side effects may include:

    • Abdominal distress
    • Abdominal pain
    • Alopecia
    • Anorexia
    • Bloating
    • Chest pain
    • Constipation
    • Decreased appetite
    • Depression
    • Diaphoresis
    • Diarrhea
    • Dizziness
    • Drowsiness
    • Dyspepsia
    • Epigastric pain
    • Fatigue
    • Gastroenteritis
    • Headache
    • Heartburn
    • Hot flash
    • Hyperhidrosis
    • Hypertension
    • Malaise
    • Nausea
    • Pancreatitis
    • Postoperative hemorrhage
    • Presyncope
    • Pruritus
    • Skin Rash
    • Swelling
    • Syncope
    • Tinnitus
    • Vertigo
    • Vomiting

    References


    Indomethacin, Philadelphia, PA: Iroko Pharmaceuticals, LLC; 2016.

    Dr Conor Sheehy
    About Dr. Conor Sheehy (Page Author)

    Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 1575

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