What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Indocin (Indomethacin)


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Generic Equivalent - Indocin (Indomethacin)

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  • Product Details


    Your doctor may prescribe indomethacin to treat different types of pain. It can be used for: moderate to severe rheumatoid arthritis, including acute flares of chronic disease, moderate to severe ankylosing spondylitis, moderate to severe osteoarthritis, acute painful shoulder, and acute gouty arthritis.

    The medication belongs to the class non-steroidal anti-inflammatory drugs (NSAIDs). These types of medication are non-narcotic pain medications and can be used for a variety of conditions.

    Fact Table




    US FDA



    Legal status


    Chemical Name


    Elimination half-life

    2.6-11.2 hours

    Dosage (Strength)

    25mg, 50mg


    Not Recommended


    Indocid, Indocin

    Protein binding


    PubChem CID






    ATC code






    Routes of administration

    By mouth


    Take Indomethacin exactly as prescribed by your doctor based on the condition being treated. The standard dosage varies from 25-50 mg up to three times daily.


    The active ingredient is indomethacin.


    There are many potential drug-drug interactions with indomethacin. Please tell your doctor and pharmacist if you are taking any of the following:

    • Acemetacin
    • Aminolevulinic Acid
    • Apixaban
    • Bemiparin
    • CycloSPORINE 
    • Dabigatran Etexilate
    • Diflunisal
    • Edoxaban
    • Enoxaparin
    • Heparin
    • Ketorolac
    • Lithium
    • Loop Diuretics
    • Macimorelin
    • Methotrexate
    • Mifamurtide
    • Nonsteroidal Anti-Inflammatory Agents
    • Phenylbutazone
    • PRALAtrexate
    • Rivaroxaban
    • Salicylates
    • Selective Serotonin Reuptake Inhibitors
    • Sincalide
    • Sodium Phosphates
    • Tenofovir Products
    • Tenoxicam
    • Tiludronate
    • Triamterene
    • Urokinase
    • Vitamin K Antagonists


    Before starting indomethacin, you should tell your doctor if you have a history of kidney disease, liver disease, heart disease, or heart failure.

    Indomethacin and other NSAIDs should only be used for the shortest amount of time at the lowest possible doses.

    Stop Indomethacin and tell your doctor right away if you develop if skin rash while taking this drug.

    Side Effects

    Some of the most common Indomethacin side effects may include:

    • Abdominal distress
    • Abdominal pain
    • Alopecia
    • Anorexia
    • Bloating
    • Chest pain
    • Constipation
    • Decreased appetite
    • Depression
    • Diaphoresis
    • Diarrhea
    • Dizziness
    • Drowsiness
    • Dyspepsia
    • Epigastric pain
    • Fatigue
    • Gastroenteritis
    • Headache
    • Heartburn
    • Hot flash
    • Hyperhidrosis
    • Hypertension
    • Malaise
    • Nausea
    • Pancreatitis
    • Postoperative hemorrhage
    • Presyncope
    • Pruritus
    • Skin Rash
    • Swelling
    • Syncope
    • Tinnitus
    • Vertigo
    • Vomiting


    Indomethacin, Philadelphia, PA: Iroko Pharmaceuticals, LLC; 2016.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 1575

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